SCHEMBL486675

SCHEMBL486675

CCCCCCCCCCCCC(CC)CCCO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.62
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.55
HSD17B10 Q99714 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
CA2 P00918 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
PTPN1 P18031 1/20 0.43
CYP3A4 P08684 2/20 0.43
OPRM1 P35372 1/20 0.42
CYP2D6 P10635 2/20 0.42
SPHK1 Q9NYA1 1/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27544762 1.00 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL11244288 1.00 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3093795 1.00 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3097270 0.98 ALDH1A1 (0.58) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3084649 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL7209399 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL11607424 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL9407934 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL728982 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL1561245 0.95 LMNA (0.62) LMNAALDH1A1TSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12064711-B2 Defoaming formulations containing organopolysiloxanes WACKER CHEMIE AG (DE) 2024-08-20 US disclosed
US-11931673-B2 Defoaming formulations containing organopolysiloxanes WACKER CHEMIE AG (DE) 2024-03-19 US disclosed
US-11925883-B2 Defoaming formulations containing organopolysiloxanes WACKER CHEMIE AG (DE) 2024-03-12 US disclosed
EP-3887015-B1 DEFOAMING FORMULATIONS CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2022-09-21 EP disclosed
CN-112334206-B Defoaming formulations comprising organopolysiloxanes 瓦克化学股份公司 2022-06-28 CN disclosed
CN-112312987-B Defoaming agent formulations containing organopolysiloxanes 瓦克化学股份公司 2022-06-17 CN disclosed
EP-3887016-B1 DEFOAMING FORMULATIONS CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2022-06-15 EP disclosed
CN-112334207-B Defoaming formulations comprising organopolysiloxanes 瓦克化学股份公司 2022-06-10 CN disclosed
EP-3887014-B1 DEFOAMING FORMULATIONS CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2022-05-11 EP disclosed
US-20220001302-A1 DEFOAMING FORMULATIONS CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2022-01-06 US disclosed
WO-2006018145-A1 ANTI-FOAMING COMPOSITIONS WACKER CHEMIE AG (DE) 2006-02-23 WO disclosed
US-20060020082-A1 Defoamer compositions WACKER-CHEMIE GMBH (DE) 2006-01-26 US disclosed
EP-1618936-A1 Defoaming compositions Wacker Chemie AG (DE) 2006-01-25 EP disclosed
CN-1724106-A Defoamer compositions WACKER CHEMIE GMBH (DE) 2006-01-25 CN disclosed
CN-1504254-A Defoaming compositions �Ϻ���ͨ��ѧ 2004-06-16 CN disclosed
US-20040106749-A1 Branched polyethersiloxane copolymer WACKER-CHEMIE GMBH (DE) 2004-06-03 US disclosed
EP-1424117-A2 Defoaming compositions Wacker-Chemie GmbH (DE) 2004-06-02 EP disclosed
US-6605183-B1 Mixtures of polysiloxanes, polyethersiloxane copolymers, emulsifiers, water and optionally preservatives or thickeners, used for defoaming pulping or papermaking solutions WACKER-CHEMIE GMBH (DE) 2003-08-12 US disclosed
EP-1076073-B1 Defoaming composition WACKER CHEMIE GMBH (DE) 2003-01-15 EP disclosed
EP-1076073-A1 Defoaming compositions Wacker-Chemie GmbH (DE) 2001-02-14 EP disclosed