Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 7/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 4/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527497 | 0.96 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16972731 | 0.91 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL995721 | 0.89 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL9100153 | 0.89 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL6136333 | 0.86 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL15655614 | 0.86 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL542258 | 0.86 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL464909 | 0.86 | GRIK1 (0.31) | SLC7A5 | |
| SCHEMBL4775852 | 0.84 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL17199754 | 0.84 | GRIK1 (0.31) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084137-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2001-03-21 | — | — | EP | claimed |
| WO-1999064442-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI S.P.A. (IT) | 1999-12-16 | — | — | WO | claimed |
| CN-104936605-A | Activin-actrii antagonists and uses for treating bone and other disorders | CELGENE CORP | 2015-09-23 | — | — | CN | disclosed |
| EP-2900686-A1 | AAV VECTORS TARGETED TO OLIGODENDROCYTES | The University Of North Carolina At Chapel Hill (US) | 2015-08-05 | — | — | EP | disclosed |
| US-7399847-B1 | Nucleic acids encoding artificial P-selectin ligands | THE GENERAL HOSPITAL CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |
| EP-0833650-A4 | P-SELECTIN LIGANDS AND RELATED MOLECULES AND METHODS | GEN HOSPITAL CORP (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-1999058640-A2 | MCT-1, A HUMAN ONCOGENE | PHILADELPHIA HEALTH AND EDUCATION CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
| EP-0833650-A1 | P-SELECTIN LIGANDS AND RELATED MOLECULES AND METHODS | THE GENERAL HOSPITAL CORPORATION (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000079-A1 | P-SELECTIN LIGANDS AND RELATED MOLECULES AND METHODS | THE GENERAL HOSPITAL CORPORATION (US) | 1997-01-03 | — | — | WO | disclosed |