Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867035 | 0.91 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL21682803 | 0.88 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL10527497 | 0.87 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL9701317 | 0.87 | GRIK1 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL17222477 | 0.87 | GRIK1 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL27990876 | 0.84 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL5707690 | 0.83 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL3512082 | 0.83 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL6239265 | 0.81 | GRIK1 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL15655614 | 0.81 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102611-A1 | HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF | Cangene Corporation (CA) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015113169-A1 | HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF | CNJ HOLDINGS, INC. (CA) | 2015-08-06 | — | — | WO | disclosed |