SCHEMBL4867110

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4863069	0.88	PDE5A (0.62)	PDE5AOGG1MAPK1POLBTAAR1
	SCHEMBL4856782	0.86	PDE5A (0.77)	PDE5AOGG1MAPK1HTTGBA1
	SCHEMBL4095293	0.83	PDE5A (1.00)	PDE5AOGG1GBA1KDM4EALDH1A1
	SCHEMBL4864327	0.83	PDE5A (0.72)	PDE5AOGG1MAPK1HTTGBA1
	SCHEMBL16404323	0.81	PDE5A (0.47)	PDE5AOGG1MAPK1HTTSMN1; SMN2
	SCHEMBL4894324	0.79	PDE5A (0.73)	PDE5AOGG1HTTSMN1; SMN2KDM4E
	SCHEMBL4864401	0.78	PDE5A (0.65)	PDE5AOGG1GBA1LMNAMAPT
	SCHEMBL16404321	0.75	MAPK1 (0.82)	PDE5AMAPK1POLBTAAR1HTT
	SCHEMBL4866829	0.75	PDE5A (0.78)	PDE5AOGG1KDM4EALDH1A1RAD52
	SCHEMBL4867367	0.75	PDE5A (0.78)	PDE5AOGG1MAPK1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.