SCHEMBL4864401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4866829	0.89	PDE5A (0.78)	PDE5ALMNAMAPTOGG1APP
	SCHEMBL4856782	0.89	PDE5A (0.77)	PDE5ALMNAGBA1OGG1APP
	SCHEMBL4864327	0.81	PDE5A (0.72)	PDE5ALMNAGBA1OGG1APP
	SCHEMBL4095293	0.79	PDE5A (1.00)	PDE5ALMNAMAPTGBA1OGG1
	SCHEMBL4864860	0.78	LMNA (0.65)	PDE5ALMNAMAPTGBA1APP
	SCHEMBL4867110	0.78	PDE5A (0.70)	PDE5ALMNAMAPTGBA1OGG1
	SCHEMBL4857481	0.78	LMNA (0.64)	PDE5ALMNAMAPTGBA1APP
	SCHEMBL4856772	0.78	GBA1 (0.82)	PDE5ALMNAMAPTGBA1APP
	SCHEMBL4867046	0.76	PDE5A (0.73)	PDE5AOGG1APPBCHEACHE
	SCHEMBL5104398	0.76	CCNE2 (0.63)	PDE5ALMNAMAPTGBA1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.