Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867654 | 1.00 | POLB (0.48) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4869484 | 0.86 | FPR1 (0.47) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4866912 | 0.83 | AVPR2 (0.56) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4863306 | 0.83 | THRB (0.42) | POLBLMNAMAPTAVPR2THRB | |
| SCHEMBL4870861 | 0.82 | AVPR2 (0.49) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4863033 | 0.81 | AVPR2 (0.48) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4867095 | 0.78 | THRB (0.53) | POLBLMNAMAPTTHRBKMT2A | |
| SCHEMBL4868697 | 0.77 | KCNQ2 (0.40) | POLBLMNAMAPTTHRBKMT2A | |
| SCHEMBL4870765 | 0.77 | AVPR2 (0.54) | POLBLMNAMAPTAVPR2AVPR1A | |
| SCHEMBL4868227 | 0.76 | POLB (0.60) | POLBLMNAMAPTAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368444-B2 | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-06 | — | — | US | claimed |