Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551944 | 0.81 | CNR1 (0.50) | NOTUMGRM2 | |
| SCHEMBL16428738 | 0.73 | NOTUM (0.46) | NOTUM | |
| SCHEMBL3551803 | 0.72 | NOTUM (0.46) | NOTUM | |
| SCHEMBL4493055 | 0.70 | CHEK1 (0.43) | — | |
| SCHEMBL3555401 | 0.68 | CNR1 (0.43) | NOTUM | |
| SCHEMBL4802594 | 0.68 | RAB9A (0.41) | NOTUM | |
| SCHEMBL1243253 | 0.67 | NOTUM (0.58) | NOTUM | |
| SCHEMBL3551392 | 0.67 | NOTUM (0.44) | NOTUM | |
| SCHEMBL3553766 | 0.67 | NOTUM (0.44) | NOTUM | |
| SCHEMBL4836554 | 0.67 | CA12 (0.42) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
| WO-2006138656-A2 | BICYCLIC HETEROCYCLES AS CANNABINOID-1 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287322-A1 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287322-A1 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | CNR1, CNR2, GPR18 | NOTUM 1607/4885GRM2 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.