Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879018 | 0.87 | MAPK14 (0.37) | DHODHALDH1A1MEN1KMT2A | |
| SCHEMBL4867590 | 0.87 | ALOX5AP (0.35) | DHODHPPARGKMOBACE1USP1 | |
| SCHEMBL4878284 | 0.87 | MAOA (0.40) | DHODHPPARGPDE10AALDH1A1HPGD | |
| SCHEMBL4866909 | 0.86 | ALOX5AP (0.35) | PPARGKMOPDE10AMEN1KMT2A | |
| SCHEMBL4873278 | 0.86 | GRIN1 (0.37) | DHODHPPARGKMOPDE10AALDH1A1 | |
| SCHEMBL4868096 | 0.85 | KDM4E (0.39) | PPARGALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4875185 | 0.84 | PPARG (0.40) | PPARGALDH1A1HPGDNPSR1 | |
| SCHEMBL4877209 | 0.84 | KDM4E (0.37) | PPARGPDE10AALDH1A1MEN1KMT2A | |
| SCHEMBL4872488 | 0.83 | KCNH2 (0.35) | PPARGMEN1KMT2A | |
| SCHEMBL4872023 | 0.82 | CYP17A1 (0.36) | DHODHPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | DHODH 1087/4885PPARG 2954/4885KMO 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.