Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867891 | 0.84 | KMT2A (0.41) | OPRM1OPRL1EPHX1MEN1KMT2A | |
| SCHEMBL16143892 | 0.81 | OPRM1 (0.45) | OPRM1OPRL1CYP2C19GPR119 | |
| SCHEMBL2987893 | 0.80 | OPRM1 (0.51) | OPRM1OPRL1CYP2C19MEN1KMT2A | |
| SCHEMBL2978912 | 0.79 | OPRM1 (0.54) | OPRM1OPRL1CYP2C19 | |
| SCHEMBL4854782 | 0.78 | OPRL1 (0.61) | OPRM1OPRL1 | |
| SCHEMBL207976 | 0.75 | OPRM1 (0.60) | OPRM1OPRL1 | |
| SCHEMBL4867137 | 0.74 | KMT2A (0.48) | OPRM1OPRL1EPHX1MEN1KMT2A | |
| SCHEMBL8693601 | 0.73 | EPHX1 (0.64) | EPHX1MEN1KMT2A | |
| SCHEMBL15127553 | 0.73 | OPRL1 (0.51) | OPRM1OPRL1 | |
| SCHEMBL4869393 | 0.72 | EPHX1 (0.42) | OPRM1OPRL1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439394-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2008-10-21 | — | — | US | claimed |
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-24 | — | — | US | claimed |
| US-7439394-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | PKD1, DDC, DPYD | OPRM1 3175/4885OPRL1 2751/4885CYP2C19 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.