Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919614 | 0.87 | SLC9A1 (0.57) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL761838 | 0.82 | SLC9A1 (0.51) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL7933277 | 0.81 | SLC9A1 (0.57) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL15339462 | 0.80 | SLC9A1 (0.53) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL17281137 | 0.75 | MGAM (0.55) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL3343750 | 0.75 | SLC9A1 (0.57) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL31067332 | 0.74 | SLC9A1 (0.59) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL253038 | 0.74 | SLC9A1 (0.59) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL14953612 | 0.74 | RPS6KA3 (0.52) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL31483490 | 0.73 | SLC9A1 (0.63) | SLC9A1GRM2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761515-B1 | 2-(HETERO-)ARYL SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-11-05 | — | — | EP | disclosed |