SCHEMBL17281137

SCHEMBL17281137

Brc1ccc(N(Cn2nnc3ccccc32)Cn2nnc3ccccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGAM O43451 3/20 0.55
AMY1A P0DUB6 3/20 0.55
GAA P10253 3/20 0.55
SI P14410 3/20 0.55
MGAM2 Q2M2H8 3/20 0.55
RAB9A P51151 2/20 0.55
PTK2 Q05397 3/20 0.51
SLC9A1 P19634 7/20 0.50
GRM2 Q14416 1/20 0.47
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
F12 P00748 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GLA P06280 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919614 0.87 SLC9A1 (0.57) MGAMAMY1AGAASIMGAM2
SCHEMBL31483490 0.77 SLC9A1 (0.63) MGAMAMY1AGAASIMGAM2
SCHEMBL4867964 0.75 SLC9A1 (0.48) MGAMAMY1AGAASIMGAM2
SCHEMBL31483489 0.75 SLC9A1 (0.61) MGAMAMY1AGAASIMGAM2
SCHEMBL7933277 0.74 SLC9A1 (0.57) MGAMAMY1AGAASIMGAM2
SCHEMBL8631037 0.74 SLC9A1 (0.59) MGAMAMY1AGAASIMGAM2
SCHEMBL283984 0.74 SLC9A1 (0.65) MGAMAMY1AGAASIMGAM2
SCHEMBL3675871 0.74 SLC9A1 (0.59) MGAMAMY1AGAASIMGAM2
SCHEMBL17125454 0.73 RAB9A (0.55) MGAMAMY1AGAASIMGAM2
SCHEMBL3343750 0.72 SLC9A1 (0.57) MGAMAMY1AGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
EP-2941474-B1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORP (JP) 2018-02-28 EP disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed