SCHEMBL4868010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16229848	0.89	EGFR (0.66)	APPSTAT1EGFRNR2F2POLB
	SCHEMBL17001434	0.88	APP (1.00)	APPEGFRNR2F2POLBBCHE
	SCHEMBL4867391	0.87	EGFR (0.67)	APPSTAT1EGFRNR2F2POLB
	SCHEMBL7500245	0.84	STAT1 (0.83)	APPSTAT1EGFRMEN1KMT2A
	SCHEMBL3112115	0.83	EGFR (1.00)	APPEGFRNR2F2POLBMEN1
	SCHEMBL4868121	0.82	MAPK1 (0.74)	APPEGFRNR2F2POLBMEN1
	SCHEMBL4074924	0.82	APP (0.67)	APPSTAT1BCHEACHEMEN1
	SCHEMBL4865169	0.82	EGFR (0.78)	APPEGFRNR2F2POLBMEN1
	SCHEMBL4859108	0.80	MAPK1 (0.76)	EGFRNR2F2POLBMEN1KMT2A
	SCHEMBL3121034	0.80	APP (0.79)	APPSTAT1BCHEACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.