SCHEMBL4868121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4865169	0.90	EGFR (0.78)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL15923256	0.87	EGFR (0.70)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL3112115	0.85	EGFR (1.00)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL11251288	0.84	LMNA (0.60)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL15923150	0.83	SMN1; SMN2 (0.59)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL15922790	0.83	SMN1; SMN2 (0.59)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL25250055	0.83	EGFR (1.00)	MAPK1SMN1; SMN2EGFRNR2F2POLB
	SCHEMBL28119990	0.83	HTT (0.67)	MAPK1SMN1; SMN2EGFRHTTCLK4
	SCHEMBL6833333	0.82	EGFR (1.00)	MAPK1SMN1; SMN2EGFRHTTCLK4
	SCHEMBL4868010	0.82	APP (0.78)	MAPK1SMN1; SMN2EGFRNR2F2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.