Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2670073 | 0.82 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL29836188 | 0.82 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL1815110 | 0.81 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL4784530 | 0.80 | ADRA2A (0.67) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL1819427 | 0.77 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL11992119 | 0.71 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL6633790 | 0.69 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL29176367 | 0.68 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL13188558 | 0.68 | SLC6A2 (0.52) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL9767993 | 0.67 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151179-A2 | SUBSTITUTED PHENETHYLAMINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-12-11 | — | — | WO | disclosed |