Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461292 | 1.00 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL29278698 | 0.98 | ADRA2A (0.66) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL4122825 | 0.81 | ADRB2 (0.50) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL2760850 | 0.81 | ADRA2A (0.66) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL9768011 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL29852847 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL7724551 | 0.80 | ADRB2 (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL4869389 | 0.80 | ADRB2 (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL7145434 | 0.79 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL28535211 | 0.78 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |