SCHEMBL486862

SCHEMBL486862

CCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCC.CCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCC.[Mo+6].[S-2].[S-2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PPARA Q07869 2/20 0.36
PPARG P37231 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
PRKCD Q05655 1/20 0.35
PAK1 Q13153 1/20 0.35
CAMK2B Q13554 1/20 0.35
CAMK2G Q13555 1/20 0.35
CAMK2D Q13557 1/20 0.35
TAOK1 Q7L7X3 1/20 0.35
TLR8 Q9NR97 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2381907 0.98 THRA (0.47) THRATHRBALOX5PTGS2TAAR1
SCHEMBL8666153 0.95 THRA (0.48) THRATHRBALOX5PTGS2TAAR1
SCHEMBL10349367 0.95 THRA (0.47) THRATHRBALOX5PTGS2TAAR1
SCHEMBL486877 0.94 THRA (0.53) THRATHRBALOX5PTGS2TAAR1
SCHEMBL486998 0.94 THRA (0.47) THRATHRBALOX5PTGS2PPARA
SCHEMBL2379852 0.92 THRA (0.55) THRATHRBALOX5PTGS2TAAR1
SCHEMBL2380344 0.92 THRA (0.48) THRATHRBALOX5PTGS2PPARA
SCHEMBL8661503 0.90 THRA (0.56) THRATHRBALOX5PTGS2PPARA
Zinc Ion SCHEMBL162803 0.89 THRA (0.55) THRATHRBALOX5PTGS2PPARA
Zinc Ion SCHEMBL8037336 0.89 THRA (0.55) THRATHRBALOX5PTGS2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208541-A2 Lubricant compositions NIPPON OIL CO. LTD. (JP) 1987-01-14 EP claimed
EP-2497819-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2017-01-04 EP disclosed
EP-2497820-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2016-06-29 EP disclosed
EP-2256181-B1 Lubricant base oil and lubricant composition for an internal combustion engine and lubricant composition for a driving force transmitting device NIPPON OIL CORP (JP) 2016-06-01 EP disclosed
US-9040470-B2 Lubricating oil composition for sliding section comprising aluminum material, and lubricating method JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-05-26 US disclosed
US-9012380-B2 Lubricant base oil, lubricant composition for internal combustion engine and lubricant composition for driving force transmitting device NIPPON OIL CORPORATION (JP) 2015-04-21 US disclosed
EP-2264134-B1 LUBRICANT OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE JX NIPPON OIL & ENERGY CORP (JP) 2014-01-29 EP disclosed
EP-1845151-B1 LUBRICANT BASE OIL, LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE AND LUBRICANT COMPOSITION FOR DRIVING FORCE TRANSMITTING DEVICE NIPPON OIL CORP (JP) 2013-11-06 EP disclosed
EP-2653528-A1 LUBRICATING OIL COMPOSITION FOR SLIDING SECTION COMPRISING ALUMINUM MATERIAL, AND LUBRICATING METHOD JX Nippon Oil & Energy Corporation (JP) 2013-10-23 EP disclosed
US-8563486-B2 Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-10-22 US disclosed
EP-2039745-A1 LUBE BASE OIL, LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE, AND LUBRICATING OIL COMPOSITION FOR DRIVE TRANSMISSION DEVICE Nippon Oil Corporation (JP) 2009-03-25 EP disclosed
EP-2009084-A1 LUBE BASE OIL, PROCESS FOR PRODUCTION THEREOF, AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2008-12-31 EP disclosed
EP-1845151-A1 LUBRICANT BASE OIL, LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE AND LUBRICANT COMPOSITION FOR DRIVING FORCE TRANSMITTING DEVICE Nippon Oil Corporation (JP) 2007-10-17 EP disclosed
US-20070207934-A1 GREASE COMPOSITION SHELL OIL COMPANY 2007-09-06 US disclosed
US-5854183-A Grease composition for constant-velocity joints NIPPON OIL CO., LTD. (JP) 1998-12-29 US disclosed
US-5585336-A MIXTURES OF OILS, UREA COMPOUND THICKENERS, MOLYBDENUM DIALKYL-DITHIOCARBAMATES AND MOLYBDENUM DIALKYL-(OR DIARYL-) DITHIOPHOSPHATES, FOR REDUCING VIBRATION SHOWA SHELL SEKIYU K.K. (JP) 1996-12-17 US disclosed
EP-0447916-B1 Engine oil composition NIPPON OIL CO LTD (JP) 1994-06-01 EP disclosed
EP-0208541-B1 LUBRICANT COMPOSITIONS NIPPON OIL CO. LTD. (JP) 1991-12-04 EP disclosed
EP-0447916-A1 Engine oil composition NIPPON OIL CO., LTD. (JP) 1991-09-25 EP disclosed
EP-0208541-A2 Lubricant compositions NIPPON OIL CO. LTD. (JP) 1987-01-14 EP disclosed