Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873124 | 0.89 | CTSS (0.55) | CTSBCTSSCTSK | |
| SCHEMBL2989322 | 0.81 | MEN1 (0.48) | L3MBTL1SIGMAR1 | |
| SCHEMBL4865061 | 0.81 | SCN9A (0.49) | CTSBCTSSCTSK | |
| SCHEMBL4864984 | 0.80 | CYP1A2 (0.44) | ALDH1A1LMNACTSBCTSSCTSK | |
| SCHEMBL2976658 | 0.80 | MEN1 (0.45) | ALDH1A1LMNASIGMAR1 | |
| SCHEMBL2985723 | 0.79 | POLB (0.40) | ALDH1A1LMNAPOLBSIGMAR1 | |
| SCHEMBL4868278 | 0.78 | SCN9A (0.53) | CTSBCTSSCTSK | |
| SCHEMBL4867979 | 0.78 | CTSK (0.48) | ALDH1A1CTSBCTSSCTSK | |
| SCHEMBL2987754 | 0.77 | POLB (0.50) | ALDH1A1LMNAPOLBRAB9ASIGMAR1 | |
| SCHEMBL4861770 | 0.76 | SCN9A (0.50) | MMP1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439394-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2008-10-21 | — | — | US | claimed |