Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474771 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ATMTDP1HCAR3MAPT | |
| SCHEMBL4868077 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ATMTDP1HCAR3MAPT | |
| SCHEMBL4863985 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ATMTDP1HCAR3MAPT | |
| SCHEMBL30135470 | 0.83 | MAPT (0.58) | ALDH1A1ATMTDP1HCAR3MAPT | |
| SCHEMBL2975856 | 0.83 | MAPT (0.58) | ALDH1A1ATMTDP1HCAR3MAPT | |
| SCHEMBL7668997 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HCAR3MAPTKCNMA1HTT | |
| SCHEMBL7173342 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HCAR3MAPTKCNMA1HTT | |
| SCHEMBL15822564 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HCAR3MAPTCYP1A2CYP3A4 | |
| SCHEMBL6541574 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HCAR3MAPTCYP1A2CYP3A4 | |
| SCHEMBL6541569 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HCAR3MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351709-B2 | Estrogen receptor ligands | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| US-20060019961-A1 | Estrogen receptor ligands | WYETH | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019961-A1 | Estrogen receptor ligands | GPER1, ESR2, ESR1 | ALDH1A1 1051/4885ATM 3819/4885TDP1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.