Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173342 | 1.00 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2MAPTPKM | |
| SCHEMBL2976885 | 0.83 | MAPT (0.58) | ALDH1A1L3MBTL1SMN1; SMN2MAPTPKM | |
| SCHEMBL4869291 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHCAR3HTTKCNMA1 | |
| SCHEMBL15822564 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHCAR3LMNA | |
| SCHEMBL6541574 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHCAR3LMNA | |
| SCHEMBL9474771 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHCAR3HTTKCNMA1 | |
| SCHEMBL6541569 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHCAR3LMNA | |
| SCHEMBL11052331 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHCAR3HTT | |
| SCHEMBL10994566 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTMAPK1TSHR | |
| SCHEMBL26634267 | 0.80 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369057-B1 | VIRICIDES, IN PARTICULAR AGAINST RETROVIRUSES, HUMAN IMMUNODEFICIENCY VIRUS (HIV) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |