Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106964 | 0.88 | HDAC1 (0.62) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL28017547 | 0.88 | HDAC1 (0.62) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL11868047 | 0.86 | HDAC1 (0.61) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL1388177 | 0.86 | HDAC1 (0.61) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL21922025 | 0.85 | HDAC1 (0.59) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL2797592 | 0.83 | LMNA (0.60) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL2794824 | 0.83 | LMNA (0.60) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL6860757 | 0.83 | HDAC1 (0.57) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL30151637 | 0.83 | LMNA (0.60) | HDAC1HDAC6LMNANPC1RAB9A | |
| SCHEMBL11554379 | 0.83 | HDAC1 (0.57) | HDAC1HDAC6LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161395-A1 | Derivatives of Aminobutanoic Acid Inhibiting Cpt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-07-03 | — | — | US | disclosed |
| EP-1853556-A1 | DERIVATIVES OF AMINOBUTANOIC ACID INHIBITING CPT | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006092204-A1 | DERIVATIVES OF AMINOBUTANOIC ACID INHIBITING CPT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161395-A1 | Derivatives of Aminobutanoic Acid Inhibiting Cpt | CPT1B, CPT1A, CPT2 | HDAC1 911/4885HDAC6 823/4885LMNA 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.