Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869095 | 0.90 | HCAR3 (0.54) | HCAR3MAPTALDH1A1GAAKDM4E | |
| SCHEMBL17673301 | 0.85 | NPSR1 (0.50) | HCAR3MAPTHTTALDH1A1GAA | |
| SCHEMBL4863985 | 0.85 | ALDH1A1 (0.47) | HCAR3MAPTHTTALDH1A1GAA | |
| SCHEMBL4868077 | 0.85 | ALDH1A1 (0.47) | HCAR3MAPTHTTALDH1A1GAA | |
| SCHEMBL6541574 | 0.82 | ALDH1A1 (0.56) | HCAR3MAPTALDH1A1KDM4EAKR1C2 | |
| SCHEMBL15822564 | 0.82 | ALDH1A1 (0.56) | HCAR3MAPTALDH1A1KDM4EAKR1C2 | |
| SCHEMBL6541569 | 0.82 | ALDH1A1 (0.56) | HCAR3MAPTALDH1A1KDM4EAKR1C2 | |
| SCHEMBL28062163 | 0.81 | KMT2A (0.53) | HCAR3MAPTALDH1A1GAAKDM4E | |
| SCHEMBL17749673 | 0.79 | HCAR3 (0.48) | HCAR3MAPTHTTALDH1A1GAA | |
| SCHEMBL17749686 | 0.79 | HCAR3 (0.48) | HCAR3MAPTHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351709-B2 | Estrogen receptor ligands | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| US-20060019961-A1 | Estrogen receptor ligands | WYETH | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019961-A1 | Estrogen receptor ligands | GPER1, ESR2, ESR1 | HCAR3 57/4885MAPT 3994/4885HTT 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.