SCHEMBL4870155

SCHEMBL4870155

[CH2]CNC(=O)C(CC)CCCC

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.63
CA1 P00915 5/20 0.63
USP2 O75604 2/20 0.55
MAPK1 P28482 2/20 0.53
TSHR P16473 3/20 0.48
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
DPP7 Q9UHL4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911707 0.84 CA2 (0.68) CA2CA1USP2MAPK1TSHR
SCHEMBL18541163 0.82 USP2 (0.66) CA2CA1USP2MAPK1TSHR
SCHEMBL5491789 0.82 USP2 (0.71) CA2CA1USP2MAPK1TSHR
SCHEMBL8458547 0.81 USP2 (0.60) CA2CA1USP2MAPK1TSHR
SCHEMBL8454582 0.81 USP2 (0.60) CA2CA1USP2MAPK1TSHR
SCHEMBL11692574 0.81 USP2 (0.69) CA2CA1USP2MAPK1TSHR
SCHEMBL22414705 0.81 USP2 (0.69) CA2CA1USP2MAPK1TSHR
SCHEMBL5323183 0.80 CA2 (0.68) CA2CA1USP2MAPK1TSHR
SCHEMBL8460512 0.79 CA2 (0.73) CA2CA1USP2MAPK1TSHR
SCHEMBL23808369 0.79 CA2 (0.61) CA2CA1USP2MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378551-B2 Amide compound KAO CORPORATION (JP) 2008-05-27 US disclosed
US-20070185208-A1 Amide compound KAO CORPORATION (JP) 2007-08-09 US disclosed
WO-2007001335-A2 RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185208-A1 Amide compound H1-0, H1-2, H1-4 CA2 4332/4885CA1 4192/4885USP2 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.