SCHEMBL487068

SCHEMBL487068

CCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCC.CCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCC.CCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCC.CCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCC.O=[Mo+4].O=[Mo+4].O=[Mo+4].[S-2].[S-2].[S-2].[S-2]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.54
THRB P10828 1/20 0.54
PPARA Q07869 3/20 0.44
PPARG P37231 2/20 0.44
LIPG Q9Y5X9 1/20 0.42
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
BID P55957 3/20 0.37
MCL1 Q07820 3/20 0.37
BCL2L1 Q07817 2/20 0.37
BAK1 Q16611 2/20 0.37
KAT8 Q9H7Z6 2/20 0.37
EP300 Q09472 1/20 0.37
KAT2A Q92830 1/20 0.37
KAT2B Q92831 1/20 0.37
KAT5 Q92993 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2380466 0.99 THRA (0.56) THRATHRBPPARAPPARGLIPG
SCHEMBL486877 0.94 THRA (0.53) THRATHRBPPARAPPARGLIPG
SCHEMBL486998 0.94 THRA (0.47) THRATHRBPPARAPPARGLIPG
SCHEMBL8661503 0.93 THRA (0.56) THRATHRBPPARAPPARGLIPG
SCHEMBL2380344 0.93 THRA (0.48) THRATHRBPPARAPPARGLIPG
Zinc Ion SCHEMBL8037336 0.93 THRA (0.55) THRATHRBPPARAPPARGLIPG
SCHEMBL4019156 0.93 THRA (0.55) THRATHRBPPARAPPARGLIPG
Zinc Ion SCHEMBL162803 0.93 THRA (0.55) THRATHRBPPARAPPARGLIPG
SCHEMBL2379852 0.93 THRA (0.55) THRATHRBPPARAPPARGLIPG
Zinc Ion SCHEMBL159097 0.93 THRA (0.55) THRATHRBPPARAPPARGLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208541-B1 LUBRICANT COMPOSITIONS NIPPON OIL CO. LTD. (JP) 1991-12-04 EP claimed
EP-0208541-A2 Lubricant compositions NIPPON OIL CO. LTD. (JP) 1987-01-14 EP claimed
EP-2497819-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2017-01-04 EP disclosed
EP-2497820-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2016-06-29 EP disclosed
EP-2256181-B1 Lubricant base oil and lubricant composition for an internal combustion engine and lubricant composition for a driving force transmitting device NIPPON OIL CORP (JP) 2016-06-01 EP disclosed
US-9040470-B2 Lubricating oil composition for sliding section comprising aluminum material, and lubricating method JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-05-26 US disclosed
US-9012380-B2 Lubricant base oil, lubricant composition for internal combustion engine and lubricant composition for driving force transmitting device NIPPON OIL CORPORATION (JP) 2015-04-21 US disclosed
EP-2264134-B1 LUBRICANT OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE JX NIPPON OIL & ENERGY CORP (JP) 2014-01-29 EP disclosed
EP-1845151-B1 LUBRICANT BASE OIL, LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE AND LUBRICANT COMPOSITION FOR DRIVING FORCE TRANSMITTING DEVICE NIPPON OIL CORP (JP) 2013-11-06 EP disclosed
EP-2653528-A1 LUBRICATING OIL COMPOSITION FOR SLIDING SECTION COMPRISING ALUMINUM MATERIAL, AND LUBRICATING METHOD JX Nippon Oil & Energy Corporation (JP) 2013-10-23 EP disclosed
US-8563486-B2 Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-10-22 US disclosed
EP-0218086-B1 LUBRICANT COMPOSITION FOR TRANSMISSION OF POWER IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-11 EP disclosed
EP-0208541-B1 LUBRICANT COMPOSITIONS NIPPON OIL CO. LTD. (JP) 1991-12-04 EP disclosed
EP-0447916-A1 Engine oil composition NIPPON OIL CO., LTD. (JP) 1991-09-25 EP disclosed
US-4704216-A OIL ADDITIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-11-03 US disclosed
US-4704215-A OIL ADDITIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-11-03 US disclosed
EP-0220426-A2 Lubricant composition for transmission of power IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-05-06 EP disclosed
EP-0218086-A2 Lubricant composition for transmission of power IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-04-15 EP disclosed
EP-0208541-A2 Lubricant compositions NIPPON OIL CO. LTD. (JP) 1987-01-14 EP disclosed
US-4501678-A CONTAINING ALKYLTHIOCARBAMOYL AND MOLYBDENUM COMPOUNDS IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-02-26 US disclosed