SCHEMBL4870724

SCHEMBL4870724

O=C(O)C(C(=O)O)C(c1ccccc1)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.45
SRC P12931 2/20 0.45
LMNA P02545 2/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 3/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
POLB P06746 1/20 0.37
KIF11 P52732 3/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1055908 0.81 CYP2D6 (0.42) CYP2D6SRCLMNAMAPK1CYP1A2
SCHEMBL1055907 0.81 CYP2D6 (0.42) CYP2D6SRCLMNAMAPK1CYP1A2
SCHEMBL6570629 0.77 LMNA (0.38) CYP2D6SRCLMNAMAPK1
SCHEMBL31356979 0.71 CYP1A2 (0.45) CYP2D6SRCLMNAMAPK1CYP1A2
Bromide SCHEMBL15753745 0.71 CYP1A2 (0.41) CYP2D6SRCLMNAMAPK1CYP1A2
SCHEMBL9286120 0.70 CYP1A2 (0.45) CYP2D6SRCLMNAMAPK1CYP1A2
Ammonia Solution, Strong SCHEMBL28512766 0.69 CYP1A2 (0.43) CYP2D6SRCLMNAMAPK1CYP1A2
SCHEMBL28327538 0.69 ESR1 (0.50) LMNA
SCHEMBL4639976 0.68 CYP1A2 (0.48) CYP2D6SRCLMNAMAPK1CYP1A2
SCHEMBL6363313 0.68 HDAC3 (0.50) CYP2D6SRCMAPK1CYP1A2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7351754-B2 Water-based ink KAO CORPORATION (JP) 2008-04-01 US disclosed
EP-1652897-A1 Water-based ink KAO CORPORATION (JP) 2006-05-03 EP disclosed
US-20040059019-A1 Water-based ink KAO CORPORATION (JP) 2004-03-25 US disclosed
EP-1375609-A2 Water-based ink KAO CORPORATION (JP) 2004-01-02 EP disclosed