Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870866 | 1.00 | NPC1 (0.54) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4870862 | 1.00 | NPC1 (0.54) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4876665 | 0.86 | NAAA (0.51) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4876650 | 0.86 | NAAA (0.51) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4876655 | 0.86 | NAAA (0.51) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4882525 | 0.83 | RAB9A (0.53) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4882531 | 0.83 | RAB9A (0.53) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4882523 | 0.83 | RAB9A (0.53) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5473357 | 0.79 | KMT2A (0.52) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5473354 | 0.79 | KMT2A (0.52) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | NPC1 239/4885MEN1 3740/4885KMT2A 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.