Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23920040 | 0.86 | AKR1C1 (0.58) | AKR1C1HDAC4NPC1MEN1KMT2A | |
| SCHEMBL27152666 | 0.86 | AKR1C1 (0.58) | AKR1C1HDAC4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23920039 | 0.84 | AKR1C1 (0.60) | AKR1C1HDAC4MEN1KMT2AKDM4E | |
| Silver SCHEMBL7493163 | 0.83 | NPC1 (0.41) | AKR1C1HDAC4NPC1BCAT2MEN1 | |
| SCHEMBL28008915 | 0.81 | AKR1C1 (0.53) | AKR1C1HDAC4MEN1KMT2AALDH1A1 | |
| SCHEMBL7226244 | 0.81 | PARP1 (0.50) | NPC1PARP1 | |
| SCHEMBL31189199 | 0.80 | AKR1C1 (0.55) | AKR1C1HDAC4MEN1KMT2AKDM4E | |
| SCHEMBL22745669 | 0.80 | AKR1C1 (0.55) | AKR1C1HDAC4MEN1KMT2AKDM4E | |
| SCHEMBL10590809 | 0.79 | NPC1 (0.44) | NPC1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3918459 | 0.78 | AKR1C1 (0.62) | AKR1C1HDAC4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640605-B1 | SPIROPYRAN COMPOUND, OPTICALLY ACTIVE SPIROPYRAN COMPOUND, AND USE THEREOF | OTSUKA KAGAKU KK (JP) | 2002-06-12 | — | — | EP | claimed |
| US-5521269-A | Spiropyran compounds and optically active spiropyran compounds and their use | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1996-05-28 | — | — | US | claimed |
| EP-0640605-A1 | SPIROPYRAN COMPOUND, OPTICALLY ACTIVE SPIROPYRAN COMPOUND, AND USE THEREOF | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | claimed |
| JP-1113350-A | — | — | None | — | — | JP | disclosed |
| JP-2032046-A | — | — | None | — | — | JP | disclosed |
| JP-2067237-A | — | — | None | — | — | JP | disclosed |
| US-20140142337-A1 | 1-AMINO-2-VINYLCYCLOPROPANE CARBOXYLIC ACID AMIDE AND SALT THEREOF, AND METHOD FOR PRODUCING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-05-22 | — | — | US | disclosed |
| EP-2725012-A1 | 1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID AMIDE, SALT OF SAME, AND METHOD FOR PRODUCING SAME | Mitsubishi Gas Chemical Company, Inc. (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1236722-B1 | Optically active 4-(tert-butoxycarbonyl) piperazine compound, and method for producing the same | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | EP | disclosed |
| EP-1227085-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR | TAKEDA PHARMACEUTICAL (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0858992-A1 | PROCESS FOR PRODUCING HALOGENATED CYCLOPROPANE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| EP-0776883-A1 | Adduct salts of substituted benzylamine and a process for optically resolving them | Ajinomoto Co., Inc. (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5521269-A | Spiropyran compounds and optically active spiropyran compounds and their use | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0640605-A1 | SPIROPYRAN COMPOUND, OPTICALLY ACTIVE SPIROPYRAN COMPOUND, AND USE THEREOF | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-5273983-A | 2-Piperidinylmethylcyclohexylaminocarbonyl-substituted benzene | LABORATORIES JACQUES LOGEAIS (FR) | 1993-12-28 | — | — | US | disclosed |
| JP-H0267237-A | PRODUCTION OF OPTICALLY ACTIVE 1,1,1-TRIFLUORO-2-ALKANOL | YAMAKAWA YAKUHIN KOGYO KK | 1990-03-07 | — | — | JP | disclosed |
| JP-H0232046-A | PRODUCTION OF OPTICALLY ACTIVE 1-METHYL-3-PHENYL-PROPYLAMINE | TORAY IND INC | 1990-02-01 | — | — | JP | disclosed |
| JP-H01113350-A | OPTICAL RESOLUTION OF (+) AND (-)-1-(4-BROMOPHENYL) ETHYLAMINE | TORAY IND INC | 1989-05-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142337-A1 | 1-AMINO-2-VINYLCYCLOPROPANE CARBOXYLIC ACID AMIDE AND SALT THEREOF, AND METHOD FOR PRODUCING SAME | ALDH7A1, ALAD, BCAT1 | AKR1C1 353/4885HDAC4 3824/4885NPC1 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.