SCHEMBL4871139

SCHEMBL4871139

NC(=O)C[C@H](NCCCO)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.39
ITGB2 P05107 2/20 0.37
ICAM1 P05362 2/20 0.37
ITGAL P20701 2/20 0.37
TGFBR1 P36897 1/20 0.37
CPB2 Q96IY4 1/20 0.36
GGT1 P19440 1/20 0.36
CA2 P00918 2/20 0.36
ALDH1A1 P00352 1/20 0.36
RAB9A P51151 1/20 0.36
CA1 P00915 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
FOLH1 Q04609 1/20 0.35
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27942118 1.00 ECE1 (0.39) ECE1ITGB2ICAM1ITGALTGFBR1
SCHEMBL7198020 0.94 ECE1 (0.38) ECE1ITGB2ICAM1ITGALTGFBR1
SCHEMBL28686534 0.93 ECE1 (0.37) ECE1ITGB2ICAM1ITGALTGFBR1
SCHEMBL1226547 0.88 ECE1 (0.41) ECE1ITGB2ICAM1ITGALTGFBR1
SCHEMBL1226550 0.88 ECE1 (0.41) ECE1ITGB2ICAM1ITGALTGFBR1
SCHEMBL1374080 0.86 ECE1 (0.36) ECE1
SCHEMBL1374076 0.86 ECE1 (0.36) ECE1
SCHEMBL2910202 0.84 CA2 (0.39) CPB2GGT1CA2TSHR
SCHEMBL2910205 0.84 CA2 (0.39) CPB2GGT1CA2TSHR
SCHEMBL28909304 0.83 ALOX15 (0.47) ECE1ITGB2ICAM1ITGALCPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270832-B2 Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation FLAMEL TECHNOLOGIES, INC. (FR) 2007-09-18 US claimed
EP-1322411-B1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECH SA (FR) 2007-01-17 EP claimed
US-20040038885-A1 Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation DEERFIELD PRIVATE DESIGN FUND II, L.P. 2004-02-26 US claimed
US-6590061-B1 Synthetic polypeptide or peptides having narrow molecular weight distribution used as telechelic polymers for synthesis of block or graft copolymers INSTITUTE OF MACROMOLECULAR CHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-07-08 US claimed
EP-1322411-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECHNOLOGIES (FR) 2003-07-02 EP claimed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP claimed
WO-2002028521-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECHNOLOGIES (FR) 2002-04-11 WO claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP claimed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed
US-20080015332-A1 Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation FLAMEL TECHNOLOGIES, INC. (FR) 2008-01-17 US disclosed
US-7270832-B2 Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation FLAMEL TECHNOLOGIES, INC. (FR) 2007-09-18 US disclosed
EP-1322411-B1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECH SA (FR) 2007-01-17 EP disclosed
US-20040038885-A1 Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation DEERFIELD PRIVATE DESIGN FUND II, L.P. 2004-02-26 US disclosed
US-6590061-B1 Synthetic polypeptide or peptides having narrow molecular weight distribution used as telechelic polymers for synthesis of block or graft copolymers INSTITUTE OF MACROMOLECULAR CHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-07-08 US disclosed
EP-1322411-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECHNOLOGIES (FR) 2003-07-02 EP disclosed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP disclosed
WO-2002028521-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR CARRYING ACTIVE PRINCIPLES AND THEIR MODE OF PREPARATION FLAMEL TECHNOLOGIES (FR) 2002-04-11 WO disclosed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP disclosed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO disclosed