SCHEMBL487142

SCHEMBL487142

CC(O)=C(O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.48
CES1 P23141 4/20 0.48
ESR1 P03372 1/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 2/20 0.43
DAO P14920 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18884554 0.81 CES2 (0.48) CES2CES1ESR1TSHRTDP1
SCHEMBL717977 0.79 TDP1 (0.56) CES2CES1TSHRTDP1MAPT
SCHEMBL6401253 0.79 TDP1 (0.56) CES2CES1TSHRTDP1MAPT
SCHEMBL6046218 0.79 TDP1 (0.56) CES2CES1TSHRTDP1MAPT
SCHEMBL3797764 0.79 ESR1 (0.50) CES2CES1ESR1TSHRTDP1
SCHEMBL3797762 0.79 ESR1 (0.50) CES2CES1ESR1TSHRTDP1
SCHEMBL688558 0.78
SCHEMBL30600022 0.77 CES1 (0.44) CES2CES1ESR1TSHRTDP1
SCHEMBL11202324 0.77 BLM (0.55) CES2CES1ESR1TSHRTDP1
SCHEMBL11202321 0.77 BLM (0.55) CES2CES1ESR1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435418-B1 A dispersant/antioxidant viscosity index improving lubricant additive TEXACO DEVELOPMENT CORP (US) 1995-01-04 EP claimed
JP-10234363-A None JP disclosed
EP-2180019-B1 Resin composition, method of its composition, and cured formulation NIPPON CATALYTIC CHEM IND (JP) 2012-02-01 EP disclosed
US-7723407-B2 mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics NIPPON SHOKUBAI CO., LTD. (JP) 2010-05-25 US disclosed
EP-2180019-A1 Resin composition, method of its composition, and cured formulation Nippon Shokubai Co., Ltd. (JP) 2010-04-28 EP disclosed
EP-1626065-A1 Resin composition, method of its composition, and cured formulation Nippon Shokubai Co., Ltd. (JP) 2006-02-15 EP disclosed
US-20060029811-A1 mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics NIPPON SHOKUBAI CO., LTD. (JP) 2006-02-09 US disclosed
JP-H10234363-A NEW ENZYME AND PRODUCTION OF PARA-HYDROXYBENZALDEHYDE DERIVATIVE, ETC., USING THE SAME CHISSO CORP 1998-09-08 JP disclosed