Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 5/20 | 0.53 |
| ▸ | CES2 | O00748 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717977 | 1.00 | TDP1 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL6046218 | 1.00 | TDP1 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL2817407 | 0.85 | TDP1 (0.50) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL216881 | 0.83 | CES1 (0.53) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL1369231 | 0.82 | TSHR (0.48) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL8066661 | 0.82 | ALDH1A1 (0.53) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL19433089 | 0.80 | CA12 (0.46) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL487142 | 0.79 | CES2 (0.48) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL18884554 | 0.79 | CES2 (0.48) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL21685 | 0.78 | HPGD (0.52) | TDP1TSHRCYP3A4MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050152978-A1 | Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds | ORADEL MEDICAL LTD. (IL) | 2005-07-14 | — | — | US | claimed |
| US-6824790-B2 | CAPSULE, TABLET WITH ENTERIC, PROTECTIVE COATINGS; BIOAVAILABILITY | ENZREL INC. | 2004-11-30 | — | — | US | claimed |
| EP-3816171-B1 | NOVEL PHOSPHACYCLIC PHOSPHITES | EVONIK OPERATIONS GMBH (DE) | 2021-12-22 | — | — | EP | disclosed |
| EP-3816171-A1 | NOVEL PHOSPHACYCLIC PHOSPHITES | Evonik Operations GmbH (DE) | 2021-05-05 | — | — | EP | disclosed |
| US-4558004-A | Monitoring preneoplastic antigen | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1985-12-10 | — | — | US | disclosed |