Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871658 | 0.80 | ACKR3 (0.47) | ACKR3KDM1AHTR6BCHEUSP30 | |
| SCHEMBL401213 | 0.75 | ACKR3 (0.49) | ACKR3HTR6BCHEUSP30KDM4E | |
| SCHEMBL5871116 | 0.67 | ACKR3 (0.67) | ACKR3KDM1AHTR6BCHEUSP30 | |
| SCHEMBL5870792 | 0.67 | ACKR3 (0.67) | ACKR3KDM1AHTR6BCHEUSP30 | |
| SCHEMBL4014855 | 0.66 | ACKR3 (0.60) | ACKR3KDM1AHTR6BCHEKDM4E | |
| SCHEMBL4013908 | 0.66 | ACKR3 (0.60) | ACKR3KDM1AHTR6BCHEKDM4E | |
| SCHEMBL4013905 | 0.66 | ACKR3 (0.60) | ACKR3KDM1AHTR6BCHEKDM4E | |
| SCHEMBL31687520 | 0.66 | ACKR3 (1.00) | ACKR3KDM1AHTR6BCHEUSP30 | |
| SCHEMBL1622524 | 0.66 | ACKR3 (0.61) | ACKR3KDM1AHTR6BCHEUSP30 | |
| SCHEMBL12722612 | 0.66 | ACKR3 (0.61) | ACKR3KDM1AHTR6BCHEUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | ACKR3 4427/4885KDM1A 4512/4885HTR6 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.