Iproheptine

Iproheptine

SCHEMBL48719

CC(C)CCCC(C)NC(C)C

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
BLM P54132 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
APEX1 P27695 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iproheptine SCHEMBL23902081 1.00 LMNA (0.46) LMNATDP1MEN1ALDH1A1HTT
Iproheptine SCHEMBL18541892 1.00 LMNA (0.46) LMNATDP1MEN1ALDH1A1HTT
Iproheptine SCHEMBL616269 0.97 LMNA (0.43) LMNATDP1MEN1ALDH1A1HTT
SCHEMBL277041 0.88 LMNA (0.50) LMNAMEN1ALDH1A1HTTKMT2A
SCHEMBL19080590 0.82 TDP1 (0.41) LMNATDP1ALDH1A1CYP1A2CYP2D6
SCHEMBL17198262 0.79 LMNA (0.42) LMNAMEN1ALDH1A1HTTKMT2A
SCHEMBL20210214 0.78 TDP1 (0.50) TDP1CYP1A2CYP2D6APEX1PMP22
SCHEMBL12201612 0.78 ADH1B (0.41) TDP1MEN1ALDH1A1KMT2A
SCHEMBL10952637 0.78 ADH1B (0.41) TDP1MEN1ALDH1A1KMT2A
SCHEMBL21118983 0.78 LMNA (0.46) LMNAMEN1ALDH1A1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372756-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2023-11-23 US claimed
WO-2023206636-A1 DELAY CIRCUIT AND SEMICONDUCTOR MEMORY 长鑫存储技术有限公司 2023-11-02 WO claimed
US-11766581-B2 Fire sprinkler with actuator TYCO FIRE PRODUCTS LP (US) 2023-09-26 US claimed
US-20220134156-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2022-05-05 US claimed
US-11291873-B2 Fire sprinkler with actuator TYCO FIRE PRODUCTS LP (US) 2022-04-05 US claimed
CN-106714911-B Controlled system and method for fire protection of stored items 泰科消防产品有限合伙公司 2021-07-30 CN claimed
US-20190314659-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2019-10-17 US claimed
US-20190209880-A1 DYNAMIC FIRE SUPPRESSION SYSTEM AND METHOD THEREOF TWIN BROOK CAPITAL PARTNERS, LLC, AS AGENT 2019-07-11 US claimed
CN-106714911-A Controlled system and method for fire protection of stored items 泰科消防产品有限合伙公司 2017-05-24 CN claimed
EP-3151928-A1 CONTROLLED SYSTEM AND METHODS FOR STORAGE FIRE PROTECTION Tyco Fire Products LP (US) 2017-04-12 EP claimed
CN-1356981-A Pharmaceutical compounds NICOX SA (FR) 2002-07-03 CN claimed
EP-1192129-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-04-03 EP claimed
EP-1169294-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-01-09 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061537-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0068743-A1 Improvements in or relating to fire fighting equipment Clements, Hubert John Topham (GB) 1983-01-05 EP claimed