Pheniramine

Pheniramine

SCHEMBL48720

CN(C)CC[C@@H](c1ccccc1)c1ccccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

HRH1

The experimentally established mechanism targets of Pheniramine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 known ✓ P35367 5/20 0.81
CHRM2 P08172 5/20 1.00
SLC6A2 P23975 5/20 1.00
SLC6A4 P31645 5/20 1.00
SCN1A P35498 3/20 1.00
SCN2A Q99250 3/20 1.00
SCN3A Q9NY46 3/20 1.00
CHRM1 P11229 4/20 0.81
SLC6A3 Q01959 4/20 0.81
KCNH2 Q12809 4/20 0.81
HRH3 Q9Y5N1 4/20 0.81
HTR2A P28223 4/20 0.81
ADRA2B P18089 3/20 0.81
LMNA P02545 3/20 0.81
TSHR P16473 3/20 0.81
CYP2D6 P10635 2/20 0.81
NFKB1 P19838 2/20 0.81
THPO P40225 2/20 0.81
DRD1 P21728 2/20 0.81
HTR2C P28335 2/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pheniramine SCHEMBL126153 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL4796 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL30182646 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL365145 0.98 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL18240052 0.98 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Chlorpheniramine SCHEMBL10622596 0.91 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Dexbrompheniramine SCHEMBL28086608 0.91 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL11615820 0.91 CHRM2 (0.83) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL14198390 0.91 CHRM2 (0.83) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Dexbrompheniramine SCHEMBL15516617 0.90 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 709 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372756-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2023-11-23 US claimed
WO-2023206636-A1 DELAY CIRCUIT AND SEMICONDUCTOR MEMORY 长鑫存储技术有限公司 2023-11-02 WO claimed
US-11766581-B2 Fire sprinkler with actuator TYCO FIRE PRODUCTS LP (US) 2023-09-26 US claimed
US-20220134156-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2022-05-05 US claimed
US-11291873-B2 Fire sprinkler with actuator TYCO FIRE PRODUCTS LP (US) 2022-04-05 US claimed
CN-106714911-B Controlled system and method for fire protection of stored items 泰科消防产品有限合伙公司 2021-07-30 CN claimed
US-20190314659-A1 FIRE SPRINKLER WITH ACTUATOR TYCO FIRE PRODUCTS LP (US) 2019-10-17 US claimed
US-20190209880-A1 DYNAMIC FIRE SUPPRESSION SYSTEM AND METHOD THEREOF TWIN BROOK CAPITAL PARTNERS, LLC, AS AGENT 2019-07-11 US claimed
CN-106714911-A Controlled system and method for fire protection of stored items 泰科消防产品有限合伙公司 2017-05-24 CN claimed
EP-3151928-A1 CONTROLLED SYSTEM AND METHODS FOR STORAGE FIRE PROTECTION Tyco Fire Products LP (US) 2017-04-12 EP claimed
US-8728197-B2 Metal nanoparticles with a pre-selected number of atoms THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-05-20 US claimed
US-8607885-B2 Fire suppressor cylinders with enhanced bubble production KIDDE TECHNOLOGIES, INC. (US) 2013-12-17 US claimed
WO-2012082612-A2 METAL NANOPARTICLES WITH A PRE-SELECTED NUMBER OF ATOMS THE GOV. OF THE U.S OF AMERICA, As Represented by THE SECRETARY OF THE NAVY (US) 2012-06-21 WO claimed
US-20120144956-A1 Metal Nanoparticles with a Pre-Selected Number of Atoms THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2012-06-14 US claimed
EP-0068743-A1 Improvements in or relating to fire fighting equipment Clements, Hubert John Topham (GB) 1983-01-05 EP claimed
US-12042682-B2 Microwave fire protection systems and methods TYCO FIRE PRODUCTS LP (US) 2024-07-23 US disclosed
EP-4382469-A1 A SYSTEM OF ELEVATOR CAB AND SHAFT DOORS FOR NARROWED SPACES Jediný, Martin (SK) 2024-06-12 EP disclosed
EP-0040211-A1 FIRE EXTINGUISHING APPARATUS. WILLEY MICHAEL ROBERT (GB) 1981-11-25 EP disclosed
EP-0029667-A1 Gas-lubricated bearings and method of manufacture Smiths Industries Public Limited Company (GB) 1981-06-03 EP disclosed
WO-1981001369-A1 FIRE EXTINGUISHING APPARATUS WILLEY M 1981-05-28 WO disclosed