SCHEMBL4872070

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4877305	0.92	GRIN2B (0.43)	GAANPSR1GRIN2BTP53
	SCHEMBL4876791	0.92	GAA (0.39)	POLBGAATSHRGRIN2BTP53
	SCHEMBL4877171	0.91	PIK3CA (0.43)	POLBGAATSHRTP53TRPV4
	SCHEMBL4872058	0.91	GAA (0.40)	POLBGAATSHRNPSR1CYP2D6
	SCHEMBL4878078	0.90	GAA (0.39)	POLBGAATSHRGRIN2BTP53
	SCHEMBL4877296	0.90	GAA (0.40)	POLBGAATSHRCYP2D6GRIN2B
	SCHEMBL4874416	0.90	TRPV4 (0.40)	POLBGAATSHRGRIN2BTRPV4
	SCHEMBL4872449	0.90	KMT2A (0.40)	POLBGAATSHRNPSR1TP53
	SCHEMBL4878287	0.89	POLB (0.41)	POLBGAATSHRNPSR1GRIN2B
	SCHEMBL4877286	0.89	POLB (0.41)	POLBGAATSHRNPSR1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.