Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872161 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL4872165 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL5469887 | 0.94 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL5469892 | 0.94 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL5470214 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL5470216 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL14194850 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL14194851 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL5466247 | 0.85 | DPP4 (0.46) | ALDH1A1MEN1KMT2ADPP4MAOB | |
| SCHEMBL5466241 | 0.85 | DPP4 (0.46) | ALDH1A1MEN1KMT2ADPP4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-20070078120-A1 | Novel piperidine derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1679069-A1 | NOVEL PIPERIDINE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | ALDH1A1 2899/4885MEN1 3740/4885KMT2A 1132/4885 |
| US-20070078120-A1 | Novel piperidine derivative | LDLR, PRMT5, MSR1 | ALDH1A1 2990/4885MEN1 3200/4885KMT2A 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.