Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469892 | 1.00 | ALDH1A1 (0.55) | ALDH1A1OPRM1OPRL1DPP4MEN1 | |
| SCHEMBL4872161 | 0.94 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1DPP4MEN1 | |
| SCHEMBL4872154 | 0.94 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1DPP4MEN1 | |
| SCHEMBL4872165 | 0.94 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1DPP4MEN1 | |
| Hydrochloric Acid SCHEMBL4880581 | 0.86 | ALDH1A1 (0.45) | ALDH1A1OPRM1OPRL1DPP4KMT2A | |
| Hydrochloric Acid SCHEMBL4880587 | 0.86 | ALDH1A1 (0.45) | ALDH1A1OPRM1OPRL1DPP4KMT2A | |
| Hydrochloric Acid SCHEMBL4880591 | 0.86 | ALDH1A1 (0.45) | ALDH1A1OPRM1OPRL1DPP4KMT2A | |
| SCHEMBL4880601 | 0.84 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL4880590 | 0.84 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL5477099 | 0.84 | ALDH1A1 (0.57) | ALDH1A1OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078120-A1 | Novel piperidine derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1679069-A1 | NOVEL PIPERIDINE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078120-A1 | Novel piperidine derivative | LDLR, PRMT5, MSR1 | ALDH1A1 2990/4885OPRM1 211/4885OPRL1 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.