Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21162820 | 0.82 | TDP1 (0.55) | TDP1CA12CA9IDO1ALDH1A1 | |
| SCHEMBL10438956 | 0.79 | CA12 (0.48) | TDP1CA12CA9ALDH1A1HSD17B10 | |
| SCHEMBL1973980 | 0.79 | CA12 (0.48) | TDP1CA12CA9ALDH1A1HSD17B10 | |
| SCHEMBL27269638 | 0.78 | TDP1 (0.50) | TDP1CA12CA9IDO1ALDH1A1 | |
| SCHEMBL42138 | 0.78 | TDP1 (0.64) | TDP1CA12CA9IDO1ALDH1A1 | |
| SCHEMBL8193205 | 0.76 | TDP1 (0.48) | TDP1CA12CA9IDO1ALDH1A1 | |
| Water SCHEMBL11613455 | 0.76 | TDP1 (0.61) | TDP1CA12CA9IDO1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7930921 | 0.76 | TDP1 (0.61) | TDP1CA12CA9IDO1ALDH1A1 | |
| SCHEMBL21586403 | 0.76 | TDP1 (0.43) | TDP1CA12CA9IDO1ALDH1A1 | |
| SCHEMBL21162821 | 0.75 | TDP1 (0.60) | TDP1CA12CA9IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110972537-B | Ablation-resistant phenolic resin composition and preparation method thereof | 华东理工大学 | 2014-07-30 | — | — | CN | claimed |
| CN-110972536-B | Preparation method of ablation-resistant phenolic resin for RTM (resin transfer molding) and phenolic resin composition | 华东理工大学 | 2014-02-12 | — | — | CN | claimed |
| EP-0549263-A2 | A process for the preparation of N-alkyl-3,4-dialkyloxyanilines and derivatives thereof | CHEMAGIS LTD. (IL) | 1993-06-30 | — | — | EP | claimed |
| US-9593197-B2 | Trigger-responsive chain-shattering polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-05-21 | — | — | US | disclosed |
| EP-2831142-A2 | TRIGGER-RESPONSIVE CHAIN-SHATTERING POLYMERS | The Board Of Trustees Of The University Of Illinois (US) | 2015-02-04 | — | — | EP | disclosed |
| CN-110972536-B | Preparation method of ablation-resistant phenolic resin for RTM (resin transfer molding) and phenolic resin composition | 华东理工大学 | 2014-02-12 | — | — | CN | disclosed |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| WO-2013173834-A2 | TRIGGER-RESPONSIVE CHAIN-SHATTERING POLYMERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-21 | — | — | WO | disclosed |
| US-8541532-B2 | Silane compound, production method thereof, and resin composition containing silane compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-2180019-B1 | Resin composition, method of its composition, and cured formulation | NIPPON CATALYTIC CHEM IND (JP) | 2012-02-01 | — | — | EP | disclosed |
| WO-2003099934-A1 | FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |
| EP-1066039-A4 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | COCENSYS INC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1073633-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-1073639-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-02-07 | — | — | EP | disclosed |
| EP-1066039-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | Cocensys, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999057098-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1999055678-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999044612-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | COCENSYS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| EP-0331357-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | SGTA, FUS, EWSR1 | TDP1 1997/4885CA12 1121/4885CA9 2513/4885 |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | ZYX, NOX3, NOXO1 | TDP1 4791/4885CA12 1733/4885CA9 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.