Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868434 | 0.93 | CBX7 (0.42) | BRD4CREBBPGRIN2BALDH1A1RAB9A | |
| SCHEMBL3931413 | 0.89 | BRD4 (0.42) | BRD4CREBBPGRIN2BALDH1A1RAB9A | |
| SCHEMBL2996625 | 0.88 | MAPK1 (0.48) | BRD4CREBBPGRIN2BALDH1A1TSHR | |
| SCHEMBL2988735 | 0.88 | MAPK1 (0.49) | BRD4CREBBPGRIN2BALDH1A1POLB | |
| SCHEMBL4875347 | 0.85 | GRIN2B (0.38) | BRD4CREBBPGRIN2BALDH1A1RAB9A | |
| SCHEMBL4872850 | 0.85 | BRD4 (0.39) | BRD4CREBBPGRIN2BALDH1A1RAB9A | |
| SCHEMBL2997044 | 0.84 | EGFR (0.48) | BRD4CREBBPGRIN2BALDH1A1POLB | |
| SCHEMBL424160 | 0.84 | PTGS2 (0.48) | GRIN2BALDH1A1RAB9ANPC1POLB | |
| SCHEMBL4878860 | 0.84 | GRIN2B (0.46) | BRD4CREBBPGRIN2BALDH1A1TSHR | |
| SCHEMBL2995706 | 0.83 | PTGS2 (0.44) | BRD4CREBBPGRIN2BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | BRD4 3577/4885CREBBP 2805/4885GRIN2B 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.