SCHEMBL4872870

SCHEMBL4872870

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nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE4A P27815 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
KDM4E B2RXH2 2/20 0.33
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865351 1.00 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL1793894 1.00 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6314530 0.98 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9689590 0.95 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8308791 0.83
SCHEMBL92768 0.82 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL215095 0.82 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL540415 0.82 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL2015790 0.82 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL14808559 0.81 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112940059-A Glycosyl modified naphthalimide-polyamine conjugate, preparation method and application thereof 河南大学 2021-06-11 CN claimed
CN-115381844-B Bacterial capsular oligosaccharide derivative, preparation method, pharmaceutical composition and application thereof 北京大学 2024-03-22 CN disclosed
WO-2023051684-A1 BACTERIAL CAPSULAR OLIGOSACCHARIDE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京大学 2023-04-06 WO disclosed
CN-112940059-B Glycosyl modified naphthalimide-polyamine conjugate, preparation method and application thereof 河南大学 2022-05-27 CN disclosed
CN-109072273-B Method for regulating protein galactosylation profile of recombinant protein by using holo-acetyl galactose 阿雷斯贸易股份有限公司 2022-04-15 CN disclosed
CN-112940059-A Glycosyl modified naphthalimide-polyamine conjugate, preparation method and application thereof 河南大学 2021-06-11 CN disclosed
EP-3455363-A1 METHODS FOR MODULATING PROTEIN GALACTOSYLATION PROFILES OF RECOMBINANT PROTEINS USING PERACETYL GALACTOSE Ares Trading S.A. (CH) 2019-03-20 EP disclosed
WO-2017194605-A1 METHODS FOR MODULATING PROTEIN GALACTOSYLATION PROFILES OF RECOMBINANT PROTEINS USING PERACETYL GALACTOSE ARES TRADING S.A. (CH) 2017-11-16 WO disclosed
US-20080224703-A1 Method and device for magnetic resonance analysis TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2008-09-18 US disclosed
US-5910579-A Processes for the preparation of αGal(1->4)βGal (1->4) Glc-OR SYNSORB BIOTECH INC. (CA) 1999-06-08 US disclosed
WO-1998030572-A1 PROCESSES FOR THE PREPARATION OF αGal(1→4)βGal(1→4)Glc-OR SYNSORB BIOTECH, INC. (CA) 1998-07-16 WO disclosed
EP-0511917-B1 Glycosylated prodrugs, process for their preparation and uses thereof HOECHST SA LAB (FR) 1996-10-23 EP disclosed
US-5561119-A ANTITUMOR AGENTS LABORATOIRES HOECHST (FR) 1996-10-01 US disclosed
EP-0511917-A1 Glycosylated prodrugs, process for their preparation and uses thereof LABORATOIRES HOECHST S.A. (FR) 1992-11-04 EP disclosed