SCHEMBL92768

SCHEMBL92768

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nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDE4A P27815 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
KDM4E B2RXH2 2/20 0.35
AKR1B1 P15121 1/20 0.32
TSHR P16473 1/20 0.32
TOP1 P11387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2015790 1.00 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL215095 1.00 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL540415 1.00 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
Ammonia Solution, Strong SCHEMBL4744785 0.98 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL14808559 0.98 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Ammonia Solution, Strong SCHEMBL2015573 0.98 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Ammonia Solution, Strong SCHEMBL482689 0.98 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7068618 0.94 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7144047 0.94 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL3864585 0.94 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063535-A Modified nucleoside containing amino derivative structure, oligonucleotide compound and synthesis method 北京安龙生物医药有限公司 2024-05-24 CN claimed
CN-116789679-A Cycloicaritin 5-glycosylation derivative and preparation method and application thereof 遵义医科大学 2023-09-22 CN claimed
US-9200026-B2 Antibacterial agents MERCK SHARP & DOHME CORP. (US) 2015-12-01 US claimed
US-20130101588-A1 NOVEL GLYCOSYLATED PEPTIDE TARGET IN NEOPLASTIC CELLS PATRYS LIMITED (AU) 2013-04-25 US claimed
JP-2011518784-A 2011-06-30 JP claimed
EP-2274425-A2 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS Alnylam Pharmaceuticals Inc. (US) 2011-01-19 EP claimed
US-7799763-B2 Muscle-strengthening drugs and anti-inflammatory drugs DAICHO KIKAKU INCORPORATED COMPANY (JP) 2010-09-21 US claimed
WO-2009126933-A2 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2009-10-15 WO claimed
EP-2101813-A2 NOVEL GLYCOSYLATED PEPTIDE TARGET IN NEOPLASTIC CELLS PATRYS LIMITED (AU) 2009-09-23 EP claimed
WO-2009023773-A9 GALACTOKINASE INHIBITORS UNIV MIAMI (US) 2009-07-30 WO claimed
US-20080199475-A1 NOVEL GLYCOSYLATED PEPTIDE TARGET IN NEOPLASTIC CELLS PATRYS LIMITED (AU) 2008-08-21 US claimed
US-20070129316-A1 MUSCLE-STRENGTHENING DRUGS AND ANTI-INFLAMMATORY DRUGS DAICHO KIKAKU INCORPORATED COMPANY (JP) 2007-06-07 US claimed
EP-0956000-A4 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF UNIV EMORY (US) 2004-06-09 EP claimed
US-6071532-A SYNTHETIC VACCINES; IMMUNOLOGY; MEDICAL DIAGNOSIS EMORY UNIVERSITY (US) 2000-06-06 US claimed
EP-0956000-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1999-11-17 EP claimed
EP-0946581-A1 THERAPEUTIC COMPOUNDS Oxford GlycoSciences (UK) Limited (GB) 1999-10-06 EP claimed
WO-1998028318-A1 THERAPEUTIC COMPOUNDS OXFORD GLYCOSCIENCES (UK) LIMITED (GB) 1998-07-02 WO claimed
WO-1998016198-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1998-04-23 WO claimed
EP-0762884-A1 MODULATORS OF PNEUMOCOCCAL ADHESION TO CELLULAR TARGETS INVOLVING THE PLATELET ACTIVATING FACTOR RECEPTOR, AND USES THEREOF THE ROCKEFELLER UNIVERSITY (US) 1997-03-19 EP claimed
WO-1995035112-A2 MODULATORS OF PNEUMOCOCCAL ADHESION TO CELLULAR TARGETS INVOLVING THE PLATELET ACTIVATING FACTOR RECEPTOR, AND USES THEREOF THE ROCKEFELLER UNIVERSITY (US) 1995-12-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129316-A1 MUSCLE-STRENGTHENING DRUGS AND ANTI-INFLAMMATORY DRUGS CYP27A1, ACHE, MYLK LMNA 829/4885L3MBTL1 4393/4885PDE4A 3446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.