Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21388380 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL3348708 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL23023473 | 0.78 | PPM1B (0.47) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL6278071 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL18378652 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL3375138 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL15508028 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL30132245 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL12375846 | 0.74 | MAPT (0.57) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL12879723 | 0.73 | MEN1 (0.48) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | CCR3, CCR1, CCR4 | SMN1; SMN2 4305/4885ALDH1A1 906/4885CYP2C9 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.