Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187928 | 0.85 | AGTR1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL709279 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL14387911 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL23828881 | 0.81 | MAOB (0.46) | SMN1; SMN2ALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL18367841 | 0.81 | ABCC9 (0.47) | SMN1; SMN2ALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL5966721 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL12879723 | 0.80 | MEN1 (0.48) | SMN1; SMN2ALDH1A1RAB9AKMT2ACYP2C9 | |
| SCHEMBL14388164 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL12523381 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KMT2AKMOCYP2C9 | |
| SCHEMBL420682 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154366-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏奥赛康药业有限公司 | 2019-08-15 | — | — | WO | disclosed |
| US-20170008910-A1 | THIAZOLOPYRROLIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008910-A1 | THIAZOLOPYRROLIDINE INHIBITORS OF ROR-GAMMA | RORC, RORB, RORA | SMN1; SMN2 4138/4885ALDH1A1 194/4885ABCC9 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.