SCHEMBL487303

SCHEMBL487303

CCCc1ccc[c]c1C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.36
DAO P14920 1/20 0.31
ELANE P08246 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2972730 0.88 LIPG (0.39)
SCHEMBL6885847 0.86 LIPG (0.46)
SCHEMBL2972440 0.84 LIPG (0.49)
SCHEMBL2972281 0.84 LIPG (0.49)
SCHEMBL7388142 0.84 LIPG (0.49)
SCHEMBL2974699 0.84 LIPG (0.49)
SCHEMBL2965736 0.84 LIPG (0.49)
SCHEMBL2972935 0.84 LIPG (0.49)
SCHEMBL218223 0.82
SCHEMBL1098793 0.81 TDP1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731954-B2 Histone demethylase inhibitors CELGENE QUANTICEL RES INC (US) 2023-08-22 US disclosed
US-20210238161-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2021-08-05 US disclosed
US-11001568-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-05-11 US disclosed
US-20200157077-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2020-05-21 US disclosed
US-10597379-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2020-03-24 US disclosed
US-10451184-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2019-10-22 US disclosed
EP-2949783-B1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR (JP) 2019-10-09 EP disclosed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed
EP-1666573-B1 LOW-FRICTION SLIDING MECHANISM AND METHOD OF FRICTION REDUCTION NISSAN MOTOR (JP) 2019-05-15 EP disclosed
US-20180319769-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2018-11-08 US disclosed
US-5597672-A Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1997-01-28 US disclosed
US-5589308-A FORMING PEELABLE TRANSFER LAYER REMOVAL UPON REACTION TREATMENT ON ELECTROGRAPHIC LIGHT SENSITIVE ELEMENT, TONER IMAGES AND HEAT EXCHANGING FUJI PHOTO FILM CO., LTD. (JP) 1996-12-31 US disclosed
US-5561014-A FORMING TONER IMAGE ON LIGHT SENSITIVE SUBSTRATE CONTAINING PEELABLE TRANSFER LAYER; RECIVER MATERIAL HAS HYDROPHILIC SURFACE SUITABLE FOR LITHOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1996-10-01 US disclosed
EP-0723985-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1996-07-31 EP disclosed
US-5501929-A TONER IMAGES ON TRANSFER LAYER OF THERMOPLASTIC RESIN FORLIGHT SENSITIVE ELEMENT FUJI PHOTO FILM CO., LTD. (JP) 1996-03-26 US disclosed
EP-0679957-A1 Method for preparation of printing plate by electrophotographic process and apparatus for use therein FUJI PHOTO FILM CO., LTD. (JP) 1995-11-02 EP disclosed
EP-0676673-A1 Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1995-10-11 EP disclosed
EP-0632338-A2 Method for preparation of printing plate by electrophotographic process and apparatus for use therein FUJI PHOTO FILM CO., LTD. (JP) 1995-01-04 EP disclosed
EP-0365118-A2 Aromatic carbonate compositions ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1990-04-25 EP disclosed
EP-0189774-B1 PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001568-B2 Histone demethylase inhibitors KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885
US-10597379-B2 Histone demethylase inhibitors KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885
US-11731954-B2 Histone demethylase inhibitors KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885
US-20180319769-A1 HISTONE DEMETHYLASE INHIBITORS KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885
US-20200157077-A1 HISTONE DEMETHYLASE INHIBITORS KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885
US-20210238161-A1 HISTONE DEMETHYLASE INHIBITORS KDM1B, KDM1A, BMI1 GRM5 2636/4885DAO 2412/4885ELANE 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.