Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972281 | 1.00 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL2972935 | 1.00 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL2974699 | 1.00 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL2972440 | 1.00 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL2965736 | 1.00 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL6885847 | 0.98 | LIPG (0.46) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL2972730 | 0.92 | LIPG (0.39) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL487303 | 0.84 | GRM5 (0.36) | — | |
| SCHEMBL21523321 | 0.81 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 | |
| SCHEMBL21523332 | 0.81 | LIPG (0.49) | LIPGKCNH2TYRBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999044989-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1999-09-10 | — | — | WO | disclosed |