Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874047 | 0.93 | TP53 (0.44) | PIK3CAMTORWNK1TP53TSHR | |
| SCHEMBL4877312 | 0.92 | PIK3CA (0.43) | PIK3CAMTORWNK1TP53TSHR | |
| SCHEMBL4876213 | 0.90 | GRM5 (0.35) | TP53MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4874611 | 0.89 | MKNK2 (0.37) | TP53MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4873028 | 0.89 | PIK3CA (0.37) | PIK3CAMTORWNK1TP53TSHR | |
| SCHEMBL4877171 | 0.89 | PIK3CA (0.43) | PIK3CAMTORWNK1TP53TSHR | |
| SCHEMBL4879108 | 0.88 | ALDH1A1 (0.41) | TP53MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4868467 | 0.88 | KDM4E (0.44) | TP53MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4874823 | 0.87 | MAPT (0.39) | TP53TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4868356 | 0.87 | MAPT (0.35) | PIK3CAMTORWNK1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | PIK3CA 1299/4885MTOR 1386/4885WNK1 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.