Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232541 | 1.00 | MMP1 (0.41) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL1105590 | 0.95 | CA1 (0.41) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL12055984 | 0.95 | CA1 (0.41) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL1109105 | 0.88 | HDAC4 (0.45) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL12064336 | 0.88 | HDAC4 (0.45) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL5934598 | 0.87 | BRD4 (0.36) | MMP1MMP3MMP9PTPN11 | |
| SCHEMBL1094800 | 0.86 | PTPN11 (0.38) | MMP1MMP3MMP9PTPN11KDM4E | |
| SCHEMBL1094798 | 0.86 | PTPN11 (0.38) | MMP1MMP3MMP9PTPN11KDM4E | |
| SCHEMBL2875736 | 0.82 | CA2 (0.49) | MMP1MMP3MMP9CA1CA2 | |
| SCHEMBL2875732 | 0.82 | CA2 (0.49) | MMP1MMP3MMP9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |