Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747354 | 0.86 | LTA4H (0.48) | CD274LTA4HALDH1A1GAAL3MBTL1 | |
| SCHEMBL4748209 | 0.85 | LTA4H (0.52) | CD274PDCD1LTA4HGAAMEN1 | |
| SCHEMBL4744478 | 0.82 | LTA4H (0.55) | CD274PDCD1LTA4HALDH1A1GAA | |
| SCHEMBL4746603 | 0.81 | ALDH1A1 (0.52) | CD274LTA4HALDH1A1GAAKDM4E | |
| SCHEMBL4746190 | 0.79 | PPARG (0.51) | CD274LTA4HALDH1A1GAAL3MBTL1 | |
| SCHEMBL4746710 | 0.78 | CD274 (0.46) | CD274PDCD1LTA4HGAACHEK2 | |
| SCHEMBL4746706 | 0.78 | CD274 (0.46) | CD274PDCD1LTA4HGAACHEK2 | |
| SCHEMBL4744385 | 0.76 | CD274 (0.54) | CD274PDCD1GAAPPARGPPARA | |
| SCHEMBL4746563 | 0.74 | FFAR1 (0.55) | CD274PDCD1LTA4HALDH1A1GAA | |
| SCHEMBL4743787 | 0.74 | PPARG (0.61) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |