SCHEMBL487383

SCHEMBL487383

CC(C)Cn1cnc2c(N)cc3cccnc3c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 5/20 0.50
HTR2A P28223 3/20 0.50
HTR2B P41595 3/20 0.50
PDE4D Q08499 2/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 2/20 0.50
HRH2 P25021 1/20 0.50
ADRA1D P25100 1/20 0.50
ADORA2A P29274 1/20 0.50
ADRA1A P35348 1/20 0.50
NUDT1 P36639 1/20 0.50
KCNH2 Q12809 1/20 0.50
HTR2C P28335 2/20 0.46
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
CYP1A2 P05177 2/20 0.42
CCNE1 P24864 1/20 0.38
CDK2 P24941 1/20 0.38
SLC29A1 Q99808 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13272016 0.83 TLR7 (0.64) TLR7HTR2AHTR2BPDE4DLMNA
Epetirimod SCHEMBL29350668 0.79 TLR7 (0.70) TLR7HTR2AHTR2BPDE4DLMNA
Epetirimod SCHEMBL29454521 0.79 TLR7 (0.70) TLR7HTR2AHTR2BPDE4DLMNA
Epetirimod SCHEMBL544542 0.79 TLR7 (0.70) TLR7HTR2AHTR2BPDE4DLMNA
SCHEMBL3195223 0.77 HTR2A (0.52) TLR7HTR2AHTR2BPDE4DLMNA
SCHEMBL544917 0.76 CCR1 (0.39) HTR2AHTR2BLMNAADRA1AHTR2C
SCHEMBL13852043 0.74 TLR7 (0.45) TLR7HTR2AHTR2BPDE4DLMNA
SCHEMBL5528022 0.74 TLR7 (0.50) TLR7HTR2AHTR2BPDE4DLMNA
SCHEMBL5495408 0.73 TLR7 (0.52) TLR7HTR2AHTR2BPDE4DLMNA
SCHEMBL2059214 0.73 TLR7 (0.69) TLR7HTR2AHTR2BPDE4DLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149907-A1 INFLUENZA VACCINES Seqirus Inc. (US) 2025-07-17 WO disclosed
CN-118488850-A Development method of peptide-based vaccine conjugated with 1V209 港大科桥有限公司 2024-08-13 CN disclosed
US-9078889-B2 Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts MEDICIS PHARMACEUTICAL CORPORATION (US) 2015-07-14 US disclosed
US-20140187575-A1 LOWER DOSAGE STRENGTH IMIQUIMOD FORMULATIONS AND SHORT DOSING REGIMENS FOR TREATING GENITAL AND PERIANAL WARTS MEDICIS PHARMACEUTICAL CORPORATION (US) 2014-07-03 US disclosed
US-8106202-B2 Method for making 1-substituted 1H-imidazo [4,5-C] quinolin-4-amine compounds and intermediates therefor FERRER INTERNACIONAL, S.A. (ES) 2012-01-31 US disclosed
EP-1879893-B1 METHOD FOR MAKING 1-SUBSTITUTED 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE COMPOUNDS AND INTERMEDIATES THEREFOR FERRER INT (ES) 2010-06-02 EP disclosed
EP-2061500-A2 PHARMACEUTICAL AND SUNSCREEN COMPOSITIONS COMPRISING CASPASE-14 VIB vzw (BE) 2009-05-27 EP disclosed
US-20090005566-A1 Method for Making 1-Substituted 1H-Imidazo [4,5-C] Quinolin-4-Amine Compounds and Intermediates Therefor FERRER INTERNACIONAL, S.A. (ES) 2009-01-01 US disclosed
WO-2008025830-A2 PHARMACEUTICAL AND SUNSCREEN COMPOSITIONS COMPRISING CASPASE-14 VIB VZW (BE) 2008-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187575-A1 LOWER DOSAGE STRENGTH IMIQUIMOD FORMULATIONS AND SHORT DOSING REGIMENS FOR TREATING GENITAL AND PERIANAL WARTS TLR3, IFNAR1, LIG3 TLR7 5/4885HTR2A 415/4885HTR2B 1221/4885
US-20090005566-A1 Method for Making 1-Substituted 1H-Imidazo [4,5-C] Quinolin-4-Amine Compounds and Intermediates Therefor CYP4B1, QARS1, CYP4F11 TLR7 1849/4885HTR2A 942/4885HTR2B 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.