Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HRH2 | P25021 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13250708 | 0.85 | TLR7 (0.59) | TLR7HTR2APDE4DPOLBHTR2B | |
| SCHEMBL16509923 | 0.84 | TLR7 (0.57) | TLR7HTR2APDE4DPOLBHTR2B | |
| SCHEMBL487383 | 0.83 | TLR7 (0.50) | TLR7HTR2APDE4DPOLBHTR2B | |
| Imiquimod SCHEMBL29357252 | 0.78 | TLR7 (1.00) | TLR7HTR2APDE4DPOLBHTR2B | |
| Imiquimod SCHEMBL570774 | 0.78 | TLR7 (1.00) | TLR7HTR2APDE4DPOLBHTR2B | |
| Imiquimod SCHEMBL26136 | 0.78 | TLR7 (1.00) | TLR7HTR2APDE4DPOLBHTR2B | |
| SCHEMBL10969308 | 0.78 | ALDH1A1 (0.46) | TLR7HTR2APDE4DPOLBHTR2B | |
| Imiquimod SCHEMBL17962753 | 0.77 | TLR7 (0.97) | TLR7HTR2APDE4DPOLBHTR2B | |
| Imiquimod SCHEMBL1301796 | 0.77 | TLR7 (0.97) | TLR7HTR2APDE4DPOLBHTR2B | |
| SCHEMBL13250709 | 0.77 | TLR7 (0.53) | TLR7HTR2APDE4DPOLBHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928485-B1 | HSP FOR USE IN TREATMENT FOR IMIQUIMOD RELATED SIDE EFFECTS | ALFA BIOGENE INT B V (DE) | 2018-04-04 | — | — | EP | disclosed |
| US-8080662-B2 | Method of preparing 4-amino-1H-imidazo (4,5-c) quinolines and acid addition salts thereof | TARO PHARMACEUTICALS U.S.A., INC. (US) | 2011-12-20 | — | — | US | disclosed |
| US-20100184984-A1 | METHOD OF PREPARING 4-AMINO-1H-IMIDAZO (4,5-C) QUINOLINES AND ACID ADDITION SALTS THEREOF | TARO PHARMACEUTICALS U.S.A. (US) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184984-A1 | METHOD OF PREPARING 4-AMINO-1H-IMIDAZO (4,5-C) QUINOLINES AND ACID ADDITION SALTS THEREOF | PAH, IL4I1, H1-5 | TLR7 458/4885HTR2A 485/4885PDE4D 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.