SCHEMBL487389

SCHEMBL487389

C=C(C)C(=O)c1[c]cccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ELANE P08246 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
EGFR P00533 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9311831 0.83 CES2 (0.46) MAPTALDH1A1CES2CES1LMNA
SCHEMBL4372441 0.79
SCHEMBL35398 0.79
SCHEMBL26572 0.79
SCHEMBL12002927 0.74 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL2651243 0.73 CES2 (0.32) MAPTALDH1A1CES2CES1LMNA
SCHEMBL1375064 0.73
SCHEMBL261633 0.73 MEN1 (0.31) MAPTMEN1KMT2A
SCHEMBL1517603 0.73
SCHEMBL143892 0.73 ALDH1A1 (0.38) ALDH1A1CES2CES1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9931611-B2 Modified hydrophobic sponges THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2018-04-03 US claimed
US-9724669-B2 Modified hydrophobic sponges THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2017-08-08 US claimed
US-20160263552-A1 MODIFIED HYDROPHOBIC SPONGES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2016-09-15 US claimed
US-20150367325-A1 MODIFIED HYDROPHOBIC SPONGES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2015-12-24 US claimed
WO-2014127179-A1 MODIFIED HYDROPHOBIC SPONGES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-08-21 WO claimed
US-8633292-B2 Polyurethane-based photochromic optical materials Signet Armorlite (US) 2014-01-21 US claimed
EP-2411848-A1 PLYURETHANE-BASED PHOTOCHROMIC OPTICAL MATERIALS Signet Armorlite Inc. (US) 2012-02-01 EP claimed
WO-2010110917-A1 PLYURETHANE-BASED PHOTOCHROMIC OPTICAL MATERIALS SIGNET ARMORLITE INC. (US) 2010-09-30 WO claimed
US-20100249264-A1 Polyurethane-based photochromic optical materials SIGNET ARMORLITE, INC. 2010-09-30 US claimed
US-11833804-B2 Visibility improving film for display panel and display device comprising same LG CHEM, LTD. (KR) 2023-12-05 US disclosed
EP-3809166-B1 ANTI-REFLECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE LG CHEMICAL LTD (KR) 2023-05-31 EP disclosed
US-11614567-B2 Low refractive layer and anti-reflective film comprising the same LG CHEM, LTD. (KR) 2023-03-28 US disclosed
US-11555947-B2 Low refractive layer and anti-reflective film comprising the same LG CHEM, LTD. (KR) 2023-01-17 US disclosed
US-11548992-B2 Antireflection film LG CHEM, LTD. (KR) 2023-01-10 US disclosed
EP-1236731-B1 Method and apparatus for forming a carbon-silicon bond in a silane GEN ELECTRIC (US) 2004-05-06 EP disclosed
US-6632585-B1 Copolymer of partially deuterated and/or halogenated vinyl siloxanes; heat, water and chemical resistance; high transmission at communication wavelength ranges NIPPON SHEET GLASS CO., LTD. (JP) 2003-10-14 US disclosed
US-6489501-B2 REACTING A TRANSITION METAL HYDRIDE WITH A STARTING SILANE SUCH AS TETRAPHENOXYSILANE IN A PRESENCE OF A CATALYST; AVOIDS USING THE COSTLY ENERGY CONSUMING REDUCTION OF SILICON DIOXIDE TO ELEMENTAL SILICON GENERAL ELECTRIC COMPANY 2002-12-03 US disclosed
US-20020161254-A1 METHOD AND APPARATUS FOR FORMING A CARBON-SILICON BOND IN A SILANE GENERAL ELECTRIC COMPANY 2002-10-31 US disclosed
EP-1236731-A1 Method and apparatus for forming a carbon-silicon bond in a silane GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP disclosed
EP-1154323-A1 PHOTOSENSITIVE COMPOSITION, AND OPTICAL WAVEGUIDE ELEMENT AND PROCESS FOR PRODUCING THE SAME Nippon Sheet Glass Co., Ltd. (JP) 2001-11-14 EP disclosed