Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 12/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.35 |
| ▸ | JUN | P05412 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183810 | 0.83 | ALDH1A1 (0.45) | MAPK10PCSK9MAPK8JUNMEN1 | |
| SCHEMBL719104 | 0.80 | MAPT (0.46) | MAPK10PCSK9MAPK8JUNCYP3A4 | |
| SCHEMBL15299233 | 0.80 | MAPK10 (0.42) | MAPK10PCSK9MAPK8JUNCYP3A4 | |
| SCHEMBL16202024 | 0.80 | MAPK10 (0.42) | MAPK10PCSK9JUNPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL5799102 | 0.78 | MAPK10 (0.41) | MAPK10PCSK9MAPK8JUNCYP3A4 | |
| SCHEMBL2555951 | 0.77 | ALDH1A1 (0.49) | MAPK10CYP3A4PSEN1PSEN2APH1B | |
| SCHEMBL13183655 | 0.77 | NOTUM (0.51) | MAPK10PCSK9MEN1ALDH1A1KMT2A | |
| SCHEMBL16202029 | 0.77 | MEN1 (0.44) | MAPK10PCSK9CYP3A4PSEN1PSEN2 | |
| SCHEMBL16202025 | 0.76 | KCNH2 (0.42) | MAPK10 | |
| SCHEMBL1955774 | 0.76 | EP300 (0.43) | MAPK10MAPK8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951713-A1 | PROCESS FOR THE LARGE SCALE PRODUCTION OF RIZATRIPTAN BENZOATE | Matrix Laboratories Ltd (IN) | 2008-08-06 | — | — | EP | claimed |
| WO-2007054979-A1 | PROCESS FOR THE LARGE SCALE PRODUCTION OF RIZATRIPTAN BENZOATE | MATRIX LABORATORIES LTD (IN) | 2007-05-18 | — | — | WO | claimed |